Stromectol (ivermectin) is a medication used to treat certain parasitic infections. Here are the key points about Stromectol:

Indications

• Treatment of intestinal strongyloidiasis due to the nematode parasite Strongyloides stercoralis
• Treatment of onchocerciasis due to the nematode parasite Onchocerca volvulus
• Treatment of crusted scabies in conjunction with topical therapy
• Treatment of human sarcoptic scabies when prior topical treatment has failed or is contraindicated

Dosage

Stromectol is available as 3 mg tablets

• The typical dosage for strongyloidiasis and onchocerciasis is 200 mcg/kg as a single dose

Mechanism of Action

• Ivermectin is derived from the avermectins, a class of highly active anti-parasitic agents
• It is a mixture containing at least 90% 5-O-demethyl-22,23-dihydroavermectin A1a

Efficacy

• In clinical trials, 64-100% of infected patients were cured following a single 200-mcg/kg dose of ivermectin for strongyloidiasis
• Patients treated with Stromectol for onchocerciasis experienced an 83.2% and 99.5% decrease in skin microfilariae after 1 and 3 months, respectively

Safety

• Stromectol is contraindicated in patients hypersensitive to any component of the product
• The most common adverse reactions include facial edema, peripheral edema, orthostatic hypotension, tachycardia, headache, and myalgia

Stromectol is a prescription medication available from a pharmacist and requires a prescription. It should be used with caution in pregnant women