By the Medsmingle Team · Updated 13 November 2026
This is a prescription medicine. Only take it if it has been prescribed for you after a medical assessment, and follow your doctor’s and pharmacist’s instructions.
Metoprolol is a beta-blocker used for high blood pressure, angina, heart failure, irregular heart rhythms and after a heart attack.
Tartrate vs succinate
- Metoprolol tartrate (Lopressor): immediate-release, usually taken twice a day
- Metoprolol succinate (Toprol XL): extended-release, once a day, and the form proven for heart failure
They aren’t simply interchangeable; your doctor decides on the form and dose.
How it works
It slows the heart rate and reduces the force of the heart’s contractions, lowering blood pressure and oxygen demand.
Side effects
- Tiredness, especially at first
- Dizziness
- Cold hands and feet
- Slow heart rate
- Sleep problems or vivid dreams
- Erection problems in some men
Don’t stop suddenly
Stopping abruptly can trigger chest pain, a fast heart rate or even a heart attack. Your doctor will set an individual tapering plan.
Cautions
- Asthma or COPD: may worsen breathing
- Diabetes: can mask a fast heartbeat from low blood sugar
- Very slow pulse, fainting or worsening breathlessness or swollen ankles: contact your doctor
Interactions
- Verapamil and diltiazem (can slow the heart too much)
- Some antidepressants such as fluoxetine and paroxetine raise levels
- Clonidine (rebound risk if stopped)
Frequently asked questions
Should metoprolol be taken with food?
Regular tablets are generally taken with or just after meals. Instructions vary by formulation; follow the label and ask your pharmacist.
For questions about a prescription or symptoms, speak with your own doctor or pharmacist. For website enquiries, contact our team.
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Medsmingle (medsmingle.com) shares clear, plain-English information on medicines and everyday health. Explore more health guides and the latest articles, read about us, or contact our team with a question.
General information only. It isn’t a substitute for advice from your doctor or pharmacist.
Source and further reading
MedlinePlus patient medicine information. This overview does not list every warning or interaction.
