By the Medsmingle Team · Updated 13 November 2026
Giloy, also called guduchi or Tinospora cordifolia, is a climbing plant that Ayurveda calls “amrita”, the root of immortality. It became especially popular as an immunity herb during the COVID-19 pandemic. It has interesting early research, but also a safety signal that’s important to know about.
Traditional uses
- Supporting immunity and recovery from fever
- Digestion
- Blood sugar balance
- Joint comfort
What the evidence shows
- Immunity: lab and animal studies show effects on immune cells, but good-quality human trials are lacking.
- Blood sugar: some small studies suggest it may lower blood sugar, which matters if you take diabetes medicine.
- Fever and infections: no reliable evidence that it treats or prevents infections like dengue or COVID-19.
The liver warning
Since 2020, doctors in India have reported cases of liver injury, including autoimmune-like hepatitis, in people taking giloy, often for several weeks or months. Many had an underlying autoimmune tendency or took other supplements too. Most recovered after stopping, but some cases were serious. LiverTox documents multiple reports, including severe injury.
Stop taking giloy and see a doctor if you notice yellow skin or eyes, dark urine, pale stools, itching or unusual tiredness.
Who should avoid it or check with a doctor first
- People with liver disease or an autoimmune condition (such as rheumatoid arthritis, lupus or type 1 diabetes)
- Anyone taking diabetes medicine, immunosuppressants or other herbal supplements
- Pregnant or breastfeeding women and children
- People having surgery in the next 2 weeks (because of blood sugar effects)
Before considering giloy
No brand or label dose guarantees safety. Discuss the liver-injury reports with a qualified healthcare professional before using it. Do not use it to prevent or treat infections or to replace prescribed medicines.
Frequently asked questions
Is giloy safe to take daily?
Safety cannot be assumed from the label or a short course. Liver injury has been reported, including serious cases. Discuss alternatives with your clinician.
Does giloy boost immunity?
It’s traditionally used for immunity, but there’s not yet good evidence in people that it prevents infections.
Can people with diabetes take giloy?
Only with a doctor’s advice, because it may lower blood sugar further when combined with diabetes medicine.
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This article is for general information only and isn’t a substitute for advice from a doctor or pharmacist. Supplements are not evaluated by the FDA to diagnose, treat, cure or prevent any disease.
