By the Medsmingle Team · Updated 13 November 2026
This is a prescription medicine. Only take it if it has been prescribed for you, and follow your doctor’s and pharmacist’s instructions.
Lisinopril is an ACE inhibitor, one of the most commonly prescribed blood pressure medicines. It’s also used for heart failure and after a heart attack, and may be prescribed in some people with diabetic kidney disease.
How it works
It relaxes blood vessels by blocking a hormone system (ACE) that narrows them, which lowers blood pressure and eases the heart’s workload.
Common side effects
- Dry, tickly cough, which can occur during treatment; tell your doctor, as switching medicines usually solves it
- Dizziness or light-headedness, especially when standing up or after the first dose
- Headache and tiredness
Serious side effects: get urgent help
- Swelling of the face, lips, tongue or throat (angioedema), even after months or years of use: call 911
- Fainting
- Signs of high potassium: muscle weakness, irregular heartbeat
Important to know
- Not safe in pregnancy: tell your doctor straight away if you’re pregnant or planning to be
- Your doctor will check potassium and kidney function with blood tests
- Avoid potassium supplements and salt substitutes unless advised
- NSAIDs like ibuprofen can reduce its effect and stress the kidneys
- Stand up slowly. If vomiting or diarrhea causes dehydration, contact your clinician for advice about fluids and medicines.
Frequently asked questions
What time of day should I take lisinopril?
At the same time each day. Many people take it in the morning; follow your doctor’s advice.
Does the lisinopril cough go away?
It usually persists while taking the medicine and goes away within weeks of stopping. Your doctor can switch you to a different type.
For questions about a prescription or symptoms, speak with your own doctor or pharmacist. For website enquiries, contact our team.
About Medsmingle
Medsmingle (medsmingle.com) shares clear, plain-English information on medicines and everyday health. Explore more health guides and the latest articles, read about us, or contact our team with a question.
This article is for general information only and isn’t a substitute for advice from a doctor or pharmacist.
Source and further reading
MedlinePlus patient medicine information. Read the leaflet for your specific medicine; this overview does not list every warning or interaction.
